Senior Director, Clinical Science

Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company developing cell therapies for patients suffering from autoimmune diseases. Guided by our core values, Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome, we are committed to transforming the future of treatment for autoimmune disease. Join us at the forefront of cell therapy innovation and help redefine what’s possible.

Title

Senior Director, Clinical Science

Location

Remote or Hybrid

Reports To

SVP, Clinical Development & Medical Affairs

### Responsibilities

• Serve as the senior clinical scientist for CAR T-cell therapy clinical trials in autoimmune disease indications, in partnership with internal and external cross-functional teams
• Partner with clinical operations, biometrics, regulatory, and commercial teams to ensure alignment on strategy and execution
• Lead design, execution, and interpretation of clinical trials across assigned program
• Provide scientific input into clinical development plans, study protocols, investigator brochures, and regulatory submissions.
• Participate in the development of clinical trial documents including protocols, ICFs, clinical development plans, and publications.
• Lead the development of clinical sections of regulatory documents including the IB, safety updates, clinical study reports, and responses to Health Authorities in collaboration with the study physician.
• Represent Clinical Development for the assigned program with cross-functional leaders
• Represent Clinical Development for the assigned program with key opinion leaders and strategic partners to inform clinical and scientific strategy
• Represent Clinical Development for the study team in high-impact external settings (advisory boards, regulatory meetings, major congresses), as appropriate
• Contribute to external scientific narrative and positioning through publications, presentat