Director, Commercial IT Systems

Location

This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis is building the commercial capabilities needed to bring new therapies to patients. We're looking for a Director of Commercial Systems to own the strategy, roadmap, and business performance of the technology supporting commercial launch and growth.

Reporting to the Vice President of Information Technology, you will lead Commercial Systems within IT. Partner with Sales, Marketing, Commercial Operations, and Market Access to translate business priorities into a coordinated roadmap, lead delivery, and ensure reliable systems and trusted data.

You will directly manage enterprise applications strategy and development and partner with IT peers, Data & Analytics, and commercial business owners. This role combines strategic leadership with accountability for delivery, reliability, launch readiness, and adoption.

Primary Responsibilities

• Own the commercial systems strategy and roadmap. Translate launch milestones and business objectives into sequenced investments, clear priorities, and measurable outcomes across CRM, commercial data, field enablement, and connected commercial platforms.
• Establish business ownership and decision-making for commercial systems. Align stakeholders on requirements, process changes, data definitions, priorities, and acceptance criteria; resolve competing demands and escalate material tradeoffs.
• Lead commercial systems delivery from planning through adoption. Coordinate internal teams and implementation partners, manage dependencies and risks, and hold owners accountable for milestones, quality, and operational readiness.
• Own business requirements and service expectations for CRM and its connections to commercial data, digital engagement, and relevant ERP workflows. Partner with enterprise application owners to ensure end-to-end processes work across organizational boun